Challenges in modern medicine
Volume 49, Issue №3, 2026
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INTERNAL DISEASES
Features of the Pathogenetic Combination of Acute Coronary Syndrome and COVID-19 Infection in Elderly Patients
Abstract. The pathogenetic combination of acute coronary syndrome (ACS) and coronavirus infection is unfavorable in terms of the development of complications and fatal outcomes. The aim of this study is to ...
Assessment of the Risk of NSAID Gastropathy in Rheumatological Patients
To date, there are no generally accepted scales for quantifying the risk of developing NSAID gastropathy. The clinical recommendations describe risk factors for its development, while scales for assessing the ...
Markers of Kidney Injury in Patients with Chronic Heart Failure of Ischemic Genesis: A Modern View on the Problem
This review explores indicators of kidney damage in individuals suffering from chronic heart failure of ischemic origin. Drawing upon contemporary scientific literature, the article highlights the principal etiological, pathogenetic, and ...
CARDIOLOGY
Clinical Case of Myocardial Infarction against the Background of Chemotherapy
This article presents a clinical case of a 64-year-old male with pancreatic adenocarcinoma who developed a large anterior myocardial infarction (MI) during mFOLFIRINOX chemotherapy. The patient experienced angina leading to ...
Neurocardial Effects of Mezodiencephalic Modulation
The article presents the results of assessing the effect of a single session of mesodiencephalic modulation on the electroencephalogram, reoencephalogram, and heart rate variability in 42 healthy volunteers. A significant ...
STOMATOLOGY
Frequency of Maxillofacial Surgery Complications in Diabetic Patients
Research into diabetes is important in terms of maxillofacial surgery, where impaired reparative processes and a susceptibility to infection can contribute to the development of complications. The aim of this ...
X-Ray Evaluation of the Membranous Canals of the Hypertrophied Shell of the Maxillary Sinus in Odontogenic Sinusitis
Hypertrophied mucosa of the maxillary sinus is a diagnostic criterion, including odontogenic maxillary sinusitis. Until now, mucosal hypertrophy as an evolutionarily conditioned compensatory mechanism necessary for maintaining homeostasis of the ...
A Review of Modern Structural Materials for the Manufacturing of Facial Epitheses
An analysis was conducted of literature sources spanning five years, focusing on construction materials for facial prostheses. Today, three groups of materials are used, depending on the manufacturing method and ...
A Modern Method of Tongue Myotonometry for Assessing its Morphofunctional State
To measure the tongue muscle tone, the tongue myotonometry method was used, which involves measuring the tongue muscle pressure on the dental arches. This method was developed to clinically assess ...
SURGERY
Combined Trauma with Thoracic Aortic Rupture
Diagnosis of a thoracic aortic rupture in cases of combined trauma is carried out by prioritizing life‑threatening conditions based on a multidisciplinary approach, taking into account the patient’s individual characteristics. ...
Association of Folic Acid Levels with Destructive Changes in the Gallbladder Wall in Elderly Comorbid Patients
The timeliness of the study is explained by high mortality rates after surgery for acute cholecystitis: while the general figure equals 1.3 %, among the elderly it increases to 25–27 ...
