Challenges in modern medicine
Volume 49, Issue №2, 2026
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INTERNAL DISEASES
Evaluation of the Influence of Irritable Bowel Syndrome on the Severity of Liver Fibrosis in Patients with Chronic Persistent Hepatitis
Objective. The study is focused on exploring the relationship between irritable bowel syndrome (IBS) and the development of liver fibrosis in patients with chronic persistent hepatitis, as well as evaluating ...
Adherence of Population with Different Socio-Economic Status to Preventive Measures in the Context of COVID-19 Pandemic
Socioeconomic status influences health and the prevalence of chronic diseases. Low-income respondents are more likely to have behavioral factors and lower levels of health literacy, which predisposes them to a ...
CARDIOLOGY
Clinical Validity of a Program for Predicting Individual Cytoprotective Efficacy of Ethylmethylhydroxypyridine Malate
To assess the clinical validity of the clinical decision support system (CDSS) "Prognostika" for predicting individual cytoprotective efficacy of ethylmethylhydroxypyridine malate (EMHP-malate) in patients with ischemic heart disease (IHD), a ...
STOMATOLOGY
Laboratory Assessment of the Elemental Composition of Dental Implant Surfaces Based on X-Ray Spectral Analysis with Mapping
Dental implantation is a current solution of dental surgery problem related to alveolar bone defects occurring after tooth extraction. The effectiveness of dental implant integration is the full osseointegration within ...
Assessment of the Psychoemotional State of Patients with Chronic Inflammatory Periodontal Diseases
High dental morbidity, especially inflammatory periodontal diseases, is aggravated by patients' fear of treatment even with the use of modern methods of anesthesia that leads to stress reactions and homeostasis ...
Current Aspects of Using Composite Colorants in Dentistry
Currently, information on the clinical use of composite colorants is formed primarily based on expert opinions and manufacturer's instructions. The lack of systematic clinical observations and publications in peer-reviewed literature ...
Lesions of the Oral Mucosa Induced by Electronic Cigarette Smoking
The use of electronic cigarettes has become an increasingly significant medical and social problem in Russia in recent years. One of the reasons for this is the decline in demand ...
Prevalence and Intensity of Dental Caries in Preschool Children of the Karachay Ethnic Group
A cross-sectional epidemiological study of the dental status was conducted in 131 preschool children (ranging from three to six years old) of the Karachay ethnic group permanently residing in the ...
SURGERY
A Clinical Case of Retrosternal Goiter
Thyroid tumors arising in the mediastinum are defined as intrathoracic goiters (the terms "retrosternal" and "intrathoracic" are used interchangeably in the literature) when the mediastinal portion is larger than the ...
Prevention of Suture Dehiscence in the Repair of Perforated Gastroduodenal Ulcer
Perforation of a gastroduodenal ulcer is a life-threatening complication of peptic ulcer disease that requires emergency surgical intervention. The most common and severe complication after suturing a perforated defect is ...
Evaluating the Efficacy of a Safety Algorithm for Laparoscopic Access in Severe Acute Appendicitis
Laparoscopic appendectomy for complicated forms of acute appendicitis remains a subject of debate due to concerns related to the high incidence of intra-abdominal abscesses. The aim of this study was ...
