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Challenges in modern medicine

Volume 49, Issue №1, 2026 PDF
INTERNAL DISEASES

Assessment of Vitamin D Availability Status and the State of Bone Mineral Density in Postmenopausal Women

The metabolism of bone tissue throughout life depends on the level of sex hormones. After menopause, there is a change in the nature of bone metabolism with a ...

Predictors of Adverse Outcomes of Traumatic Brain Injury

The aim of the study is to identify prognostic predictors of adverse outcomes of moderate traumatic brain injury (TBI). The study included 199 patients with adverse outcomes of TBI. ...

The State of Microbiocenosis of the Large Intestine in Children against the Background of Systemic Therapy with an Antimycotic

The study was aimed at evaluating the effect of a tablet antimycotic on the normal flora of the large intestine in the treatment of scalp microsporium in children. Materials and ...
STOMATOLOGY

The Effect of Glucocorticosteroids on the Osseointegration of Dental Implants: Pathogenetic Mechanisms and Clinical Consequences

Glucocorticosteroids (GCS) have a complex effect on bone metabolism, theoretically creating risks for dental implant osseointegration through glucocorticoid-induced osteoporosis (GIOP). Aim: to analyze the pathogenetic mechanisms of GCS effect ...

Microbiological Analysis of the Microbial Community of the Root Canal System in Chronic Apical Periodontitis

Chronic apical periodontitis is an inflammatory disease of the tissues surrounding the tip of the tooth root, characterized by destruction of bone tissue and often asymptomatic. For a ...
SURGERY

Endobiliary Stenting of Perpapillary Tumor Obstruction Using Digital Modeling of a Coated Self-Expanding Stent

Endobiliary stenting of the peripapillary tumor obstruction zone suggests the development of ascending cholangitis. Objective: To study the antireflux effect of biliary stenting as a factor in the ...

The Role of Time Control in the Quality of Cardiac Surgery Treatment: Problem Statement

The surgical treatment protocols recommended by professional communities today do not include indicators of the duration of the operation stages and inter-stage intervals, although they are necessary for ...

Modern Minimally Invasive Method of Treating a Rare Complication after Laparoscopic Refundoplication with Alloplasty

Surgical treatment of patients with hiatal hernias most often involves laparoscopic fundoplication. According to various literature sources, this method has a recurrence rate of 10 % to 50 %. ...