Challenges in modern medicine
Volume 48, Issue №4, 2025
PDF
INTERNAL DISEASES
Clinical and Pathogenetic Aspects of Atherosclerosis and Non-Alcoholic Fatty Liver Disease
The paper presents the results of a comprehensive analysis of scientific publications in international peer-reviewed journals for the period 2010-2025. The authors used a systematic approach to search, ...
Clinical Manifestations of Post-COVID Syndrome and the Role of Genes in their Development in Patients with Arterial Hypertension and Obesity
Though arterial hypertension (AH) and obesity (O) exacerbate the course of acute respiratory syndrome coronavirus 2 (SARS-CoV-2), their contribution to the development of post-COVID syndrome has been insufficiently studied. ...
Safety and Effectiveness of Lanadelumab in Long-Term Prevention of Hereditary Angiooedema
The purpose of this work is to review the results of modern studies on the effectiveness and safety of lanadelumab, a new drug for biological targeted therapy of ...
CARDIOLOGY
Secondary Arterial Hypertension in Patients with a Neuroendocrine Tumor of the Adrenal Glands
The article aims to stress the importance of revealing the causes of arterial hypertension (AH) and providing differential diagnostics. Being a globally spread issue that is discussed by ...
STOMATOLOGY
Analysis of Wear Resistance of Temporary Filling Materials
Temporary tooth fillings are applied for 14 days, on average. If the integrity of the filling is violated, it disintegrates, and a space is formed between the temporary ...
A Modern View of the Etiopathogenesis, Diagnosis, and Treatment of Bruxism
Bruxism is a parafunctional chewing activity consisting in an involuntary clenching or grinding of teeth, which can occur both during sleep and while awake. The etiology of bruxism ...
Small Oral Vestibule and a Method for its Correction
The article presents clinical cases of patients with a small oral vestibule, which is a mucogingival anomaly. Mucogingival abnormalities are among the pressing issues of dentistry. Mucogingival anomalies ...
Prevalence of Apical Periodontitis in the Belgorod Agglomeration
In most cases, apical periodontitis is a complication of untreated pulpitis or its unsuccessful treatment resulting from the complex anatomy of the root canals or their sclerosis. The ...
SURGERY
Neural Network Classification of the Type of Ulcerative Gastroduodenal Bleeding According to Endoscopic Images
Ulcerative gastroduodenal bleeding remains a serious problem in modern medicine. To determine the type of ulcerative bleeding, the Forrest classification is used worldwide, defining the tactics of treating patients ...
Colotomy for Colonic Foreign Body Retrieval: How to Finish the Operation?
The study is devoted to the analysis of complications in patients with foreign objects in the colon (FOC) who underwent surgical treatment to remove the foreign body. The ...
OBITUARY
In Memory of Alexander Viktorovich Tsimbalistov. Obituary and Condolences
Александр Викторович Цимбалистов (22 сентября 1948 – 24 ноября 2025) 24 ноября 2025 года ушел из жизни наш коллега, соратник, известный российский ученый, специалист в области стоматологии, Заслуженный врач ...
