Effect of antioxidant therapy on arrhythmia in patients with acute myocardial infarction after percutaneous transluminal coronary intervention
The dynamics of arrhythmia indicators in patients with acute myocardial infarction, after percutaneous transluminal coronary intervention in 2 comparison groups; with and without the addition of antiacidemic therapy to standard treatments was studied.The study included 56 patients with acute myocardial infarction and the presence of supraventricular and ventricular extrasystoles according to the results of primary electrocardiography followed by coronary stenting. The age of patients from 39 to 74 years old, hospitalized in the infarction department from 2018 to 2020 in the district hospital No 2 of Makhachkala. After admission to the hospital and stenting, all patients underwent the following types of examination on the 2nd day and again after 10 days; daily monitoring of electrocardiography, echocardiography and determined the pH of the blood. The patients were randomized and assigned to 2 groups based on the selection.The results of daily monitoring of electrocardiography showed that in the 1st group with the addition of sodium bicarbonate, there was a significant decrease in supraventricular extrasystole by 70.6 % and ventricular extrasystole - 63.6 %. The duration of episodes supraventricular paroxysmal tachycardia by72.6 % and atrial fibrillation - 76.6 %, respectively, p < 0.05.In the 2nd group, arrhythmias also significantly decreased supraventricular extrasystole - 45.8 % and ventricular extrasystole - 50.0 %. The duration of episodes of supraventricular paroxysmal tachycardia by% and atrial fibrillation - 61.4 %, respectively, p < 0.05.The study showed that the additional administration of sodium bicarbonate in the acute period of myocardial infarction after coronary stenting effectively eliminates cardiac arrhythmias. This result is achieved by improving the acid-base balance of the myocardium, pathways and ectopic nodes.
Khabchabov R.G., Makhmudova E.R., Dzhanbulatov M.A. 2021. The effect of antiacidemic therapy on arrhythmia in patients with acute myocardial infarction after percutaneous transluminal coronary intervention. Challenges in Modern Medicine. 44 (2): 174–182 (in Russian). DOI: 10.52575/2687-0940-2021-44-2-174-182.
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