REMODELING OF THE LEFT VENTRICULAR MYOGARDIUM WITH RHEUMATOID ARTHRITIS, FACTORS INFLUENCING IT
The purpose of the work is to study the various types frequency of left ventricular geometry among patients with rheumatoid arthritis, as well as factors that influence it’s development in this cohort. 140 patients with rheumatoid arthritis were examined. The average age is 53.8 years, women – 82.1 %, men – 17.9 %. The comparison group included 40 patients with essential hypertension without rheumatoid arthritis. The observation group revealed a high frequency of pathological forms of the geometry of the left ventricle when compared with the comparison group. Left ventricular hypertrophy among women with RA was recorded 1.4 times more often than among men. In patients with rheumatoid arthritis and arterial hypertension the concentric type of hypertrophy was more common than in patients without hypertension (41.2 % versus 28.5 %). Factors accompanied by an increase in the frequency of left ventricular hypertrophy were also: rheumatoid factor seropositivity (82 % versus 36 % among seronegative ones), decreased renal filtration function (with a glomerular filtration rate of less than 60 ml/min/1.73 m2, the hypertrophy rate was 100 %, and with values of more than 90 ml/min/1.73 m2 – 50 %).
Otarova Zh.Z., Eliseeva L.N., Zhdamarova O.I., Davydova N.N., Shuhardina E.L. 2020. Remodeling of the left ventricular myogardium with rheumatoid arthritis, factors influencing it. Challenges in Modern Medicine, 43(1): 16–27 (in Russian). DOI
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