A Modern View of the Etiopathogenesis, Diagnosis, and Treatment of Bruxism
Bruxism is a parafunctional chewing activity consisting in an involuntary clenching or grinding of teeth, which can occur both during sleep and while awake. The etiology of bruxism has a complex multifactorial basis. Despite the apparent simplicity of manifestation, the mechanisms of bruxism are very complex and still not fully understood. Scientists are actively studying the role of the central nervous system in this process. The use of modern neurophysiological research methods, such as electromyography, polysomnography, allows obtaining more accurate data on the neural processes underlying bruxism. Despite numerous studies, many questions about the etiology, pathophysiological mechanisms and treatment of bruxism remain open and require further research. The aim of the study is to collect and analyze information about bruxism; to study the mechanisms of its occurrence and neurophysiological features for a deeper understanding of the neural connections that control bruxism; to determine clinical manifestations and risk factors associated with bruxism; to evaluate the effectiveness of various diagnostic methods and modern approaches to the treatment of bruxism. For this purpose, we explored modern domestic and foreign literature included in Scopus, RINTS, PubMed.
Kostrigina E.D., Efremova A.S., Efremova D.S., Krechkevich A.I. 2025. A Modern View of the Etiopathogenesis, Diagnosis, and Treatment of Bruxism. Challenges in Modern Medicine, 48(4): 493–502 (in Russian). DOI: 10.52575/2687-0940-2025-48-4-493-502. EDN: SGQAQR




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Antonova I.N., Barmashov S.N., Nechkin S.B. 2023. Bruxism: Etiology, Pathogenesis, Diagnostics, Approaches to Treatment. Modern dentistry. 2(91): 8–13 (in Russian).
Kavetsky V.P., Dolin V.I. 2021. Features of Clinical Manifestations of Bruxism in the Oral Cavity. Modern Dentistry. 3(84): 27–31 (in Russian).
Clinical Guidelines. Bruxism. 2023. 9–46 (in Russian). https://oblstom.ru/wp-content/uploads/2025/02/014_bruksizm.pdf
Kulish E.A. 2023. Bruxism as an Interdisciplinary Problem. Young Scientist. 34(481): 36–38 (in Russian).
Menshikova A.A. 2021. The Role of Psychosomatic and Psychosocial Factors in the Occurrence of Bruxism. Bulletin of Science. 2(35): 206–208 (in Russian).
Seliverstov Yu.A., Belopasova A.V. 2020. Expanding the Horizons of Botulinum Therapy in Clinical Neurology. Bulletin of the National Parkinson's Disease and Movement Disorders Society. 1: 3–6 (in Russian). doi: 10.24411/2226-079X-2020-12167
Terentyeva E.V., Dubinskaya A.D., Yurova O.V. 2024. Modern View on the Etiology and Methods of Treatment of Bruxism: Review. Bulletin of Restorative Medicine. 6: 121–125 (in Russian). doi: 10.38025/2078-1962-2024-23-6-119-129
Chernyshov I.I. 2018. Bruxism, General Characteristics and Diagnostic Methods. BMIK. 4: 153–155 (in Russian). ID: 2018-04-5-A-16941
Anghel L., Ciubară A., Nechita A., Nechita L., Manole C., Baroiu L., Ciubară A.B., Mușat C.L. 2023. Sleep Disorders Associated with Neurodegenerative Diseases. Diagnostics (Basel). 13(18): 2898. doi: 10.3390/diagnostics13182898
Boscato N., Exposto F.G., Costa Y.M., Svensson P. 2022. Effect of Standardized Training in Combination with Masseter Sensitization on Corticomotor Excitability in Bruxer and Control Individuals: A Proof of Concept Study. Sci Rep. 12(1): 17469. doi: 10.1038/s41598-022-21504-w
Chemelo V.D.S., Né Y.G.S., Frazão D.R., de Souza-Rodrigues R.D., Fagundes N.C.F., Magno M.B., da Silva C.M.T., Maia L.C., Lima R.R. 2020. Is There Association Between Stress and Bruxism? A Systematic Review and Meta-Analysis. Front Neurol. 11: 590779. doi: 10.3389/fneur.2020.590779
George S., Joy R., Roy A. 2021. Drug-Induced Bruxism: A Comprehensive Literature Review. Journal of Advanced Oral Research. 12(2): 232020682199253. doi: 10.1177/2320206821992534
Kothari S.F., Devendran A., Sorensen A.B., Nielsen J.F., Svensson P., Kothari M. 2024. Occurrence, Presence and Severity of Bruxism and its Association with Altered State of Consciousness in Individuals with Severe Acquired Brain Injury. Journal of Oral Rehabilitation 51(1): 143–149. doi: 10.1111/joor.13540
Kuang B., Aarab G., Wei Y., Blanken T.F., Lobbezoo F., Van Someren E.J.W., Ramautar J.R., Wassing R. 2023. Associations between Signs of Sleep Bruxism and Insomnia: A Polysomnographic Study. J Sleep Res. 32(4): e13827. doi: 10.1111/jsr.13827
Minervini G., Franco R., Marrapodi M.M., Ronsivalle V., Shapira I., Cicciù M. 2023. Prevalence of Temporomandibular Disorders in Subjects Affected by Parkinson Disease: A Systematic Review and Metanalysis. J Oral Rehabil. 50(9): 877–885. doi: 10.1111/joor.13496
Ohlmann B., Waldecker M., Leckel M., Bömicke W., Behnisch R., Rammelsberg P., Schmitter M. 2020. Correlations between Sleep Bruxism and Temporomandibular Disorders. J Clin Med. 9(2): 611. doi: 10.3390/jcm9020611
Raja H.Z., Saleem M.N., Mumtaz M., Tahir F., Iqbal M.U., Naeem A. 2024. Diagnosis of Bruxism in Adults: A Systematic Review. J Coll Physicians Surg Pak. 34(10): 1221–1228. doi: 10.29271/jcpsp.2024.10.1221
Sarkar A.K., Nakamura S., Nakai K., Sato T., Shiga T., Abe Y., Hoashi Y., Inoue T., Akamatsu W., Baba K. 2022. Increased Excitability of Human iPSC-derived Neurons in HTR2A Variant-Related Sleep Bruxism. Stem Cell Res. 59(1): 102658. doi: 10.1016/j.scr.2022.102658
Verhoeff M.C., Koutris M., Berendse H.W., van Dijk K.D., Lobbezoo F. 2022. Parkinson's Disease, Temporomandibular Disorder Pain and Bruxism and its Clinical Consequences: A Protocol of a Single-Centre Observational Outpatient Study. BMJ Open. 12(4): e052329. doi: 10.1136/bmjopen-2021-052329
Vieira M.A., Oliveira-Souza A.I.S., Hahn G., Bähr L., Armijo-Olivo S., Ferreira A.P.L. 2023. Effectiveness of Biofeedback in Individuals with Awake Bruxism Compared to Other Types of Treatment: A Systematic Review. Int J Environ Res Public Health. 20(2): 1558. doi: 10.3390/ijerph20021558
Yang S.H., Yang E., Lee J., Kim J.Y., Yoo H., Park H.S., Jung J.T., Lee D., Chun S., Jo Y.S., Pyeon G.H., Park J.Y., Lee H.W., Kim H. 2023. Neural Mechanism of Acute Stress Regulation by Trace Aminergic Signalling in the Lateral Habenula in Male Mice. Nat Commun. 14: 2435. doi: 10.1038/s41467-023-38180-7
Zhao Y.J., Liu Y., Wang J., Li Q., Zhang Z.M., Tu T., Lei R., Zhang M., Chen Y.J. 2022. Activation of the Mesencephalic Trigeminal Nucleus Contributes to Masseter Hyperactivity Induced by Chronic Restraint Stress. Front Cell Neurosci. 16: 841133. doi: 10.3389/fncel.2022.841133
Zieliński G., Pająk A., Wójcicki M. 2024. Global Prevalence of Sleep Bruxism and Awake Bruxism in Pediatric and Adult Populations: A Systematic Review and Meta-Analysis. J Clin Med. 13(14): 4259. doi: 10.3390/jcm13144259