Modeling of Craniofacial Lesions, Analysis of Regeneration Time and Indications for Surgical Correction
The purpose of the experiment. Experimental modeling of craniofacial injuries, analysis of oculomotor function and regeneration in the post-traumatic period. Materials and methods. In the experiment, 48 sexually mature males of the Wistar breed were hit with a blunt hammer on a pre-determined area on the muzzle. According to the MS CT data, the nature of the displacement of bone fragments and the presence of muscle interposition were visualized. In the post-traumatic period, behavioral activity in the Actimeter device was analyzed. Results and discussion. Taking into account the thickness of the bone, the localization of the buttress at the place of applied force in the rodent, the hypothesis of energy absorption with its propagation through the bone structures of the orbits, and their subsequent displacement, was confirmed. Conclusions. In 38% of animals (groups 2 and 4), after impact to the postero lateral segment of the lower wall of the orbit, type 2 fracture of the cheekbone-orbital complex was recorded. In the post-traumatic period, a violation of behavioral activity was registered, which required prompt correction of displaced fragments. Upon impact to the central segment, in 50% of cases, 1 type of fracture was formed, without deviations in behavioral activity and without the need for surgical treatment.
Gandylyan K.S., Lebedev P.R., Gabbasova I.V., Sletova V.A., Dedikov D.N., Kononenko V.I., Osmaev U.M., Sletov A.A. 2024. Modeling of Craniofacial Lesions, Analysis of Regeneration Time and Indications for Surgical Correction. Challenges in Modern Medicine, 47(3): 316–327 (in Russian). DOI: 10.52575/2687-0940-2024-47-3-316-327
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The work was carried out without external sources of funding.