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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Актуальные проблемы медицины</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2687-0940-2020-43-4-473-489</article-id><article-id pub-id-type="publisher-id">47</article-id><article-categories><subj-group subj-group-type="heading"><subject>ВНУТРЕННИЕ БОЛЕЗНИ</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;Клинико-лучевые и морфологические особенности COVID-19 ассоциированной пневмонии в динамике заболевания&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;Clinical radiation and morphological features of COVID-19 associated pneumonia in the dynamics of the disease&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Ходош</surname><given-names>Эдуард Михайлович</given-names></name><name xml:lang="en"><surname>Khodosh</surname><given-names>Eduard M.</given-names></name></name-alternatives><email>gen.khodosh@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Грифф</surname><given-names>Сергей Леонидович</given-names></name><name xml:lang="en"><surname>Griff</surname><given-names>Sergey L.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Ивахно</surname><given-names>Игорь Владимирович</given-names></name><name xml:lang="en"><surname>Ivakhno</surname><given-names>Igor V.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="epub"><year>2020</year></pub-date><volume>43</volume><issue>4</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2020/4/473-489.pdf" /><abstract xml:lang="ru"><p>Человечеству объявлена война, инициатором и врагом которой стало новое заболевание, вызванное коронавирусом (РНК SARS Cov-2). Победа в этой войне, то есть выживание и выздоровление каждого больного зависит от решения многих научных, технических, организационных и клинических проблем, в частности более оптимального понимания морфологической и клинико-лучевой картины данного заболевания. Первоначальная диагностическая гипотеза при COVID-19 основана на гриппоподобном состоянии и молекулярных тестах, таких как полимеразная цепная реакция (RT-PCR) методом секвенирования. Однако эти тесты могут быть ложноположительными или ложноотрицательными (до 30 %), а также недоступны в неотложных ситуациях. Поэтому клиническая симптоматика в контексте лучевой и морфологической диагностики используется в качестве важного маркера для выявления этиологии COVID-19 ассоциированной пневмонии в нынешних эпидемиологических условиях</p></abstract><trans-abstract xml:lang="en"><p>War has been declared to mankind, the initiator and enemy of which has become a new disease caused by the coronavirus (SARS Cov-2 RNA). Victory in this war, that is, the survival and recovery of&amp;nbsp;&amp;nbsp;each patient depends on the solution of many scientific, technical, organizational and clinical problems, in particular, a more optimal understanding of the morphological and clinical-radiation picture of this disease. The initial diagnostic hypothesis for COVID-19 is based on an influenza-like condition and molecular tests such as polymerase chain reaction (RT-PCR) sequencing. However, these tests can be false positive or false negative (up to 30 %) and are not available in emergency situations. Therefore, clinical symptoms in the context of radiological and morphological diagnostics are used as an important marker for identifying the etiology of COVID-19 associated pneumonia in the current epidemiological conditions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пневмония</kwd><kwd>ПЦР</kwd><kwd>компьютерная томограмма</kwd><kwd>матовое стекло</kwd><kwd>ретикулярный паттерн</kwd><kwd>фиброз</kwd><kwd>организующаяся пневмония</kwd><kwd>микротромбоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pneumonia</kwd><kwd>PCR</kwd><kwd>computed tomography</kwd><kwd>ground glass</kwd><kwd>reticular pattern</kwd><kwd>fibrosis</kwd><kwd>organizing  pneumonia</kwd><kwd>microthrombosis</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Вступительное слово Генерального директора ВОЗ на брифинге для СМИ по COVID-19 - 11 марта 2020 г. https://www.who.int/ru/director-general/speeches/detail/who-director-general-s-openingremarks-at-the-media-briefing-on-COVID-19---11-may-2020 (по состоянию на 22 марта 2020 г.).</mixed-citation></ref><ref id="B2"><mixed-citation>Справочник по профилактике и лечению COVID-19. 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