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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Актуальные проблемы медицины</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.52575/2687-0940-2022-45-3-263-272</article-id><article-id pub-id-type="publisher-id">122</article-id><article-categories><subj-group subj-group-type="heading"><subject>КАРДИОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;Хроническая ишемическая болезнь сердца. Кто нуждается в усилении антитромботической терапии?&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;Chronic&lt;/strong&gt; &lt;strong&gt;Coronary&lt;/strong&gt; &lt;strong&gt;Heart&lt;/strong&gt; &lt;strong&gt;Disease&lt;/strong&gt;&lt;strong&gt;.&amp;nbsp;&lt;/strong&gt;&lt;strong&gt;Who Needs Enhanced Antithrombotic Therapy?&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Панина</surname><given-names>Юлия Николаевна</given-names></name><name xml:lang="en"><surname>Panina</surname><given-names>Yulia N.</given-names></name></name-alternatives><email>doc.panina@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Вишневский</surname><given-names>Валерий Иванович</given-names></name><name xml:lang="en"><surname>Vishnevskij</surname><given-names>Valery I.</given-names></name></name-alternatives><email>vishnevsky.orel@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Громнацкий</surname><given-names>Николай Ильич</given-names></name><name xml:lang="en"><surname>Gromnatskij</surname><given-names>Nikolai I.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="epub"><year>2022</year></pub-date><volume>45</volume><issue>3</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2022/3/263-272.pdf" /><abstract xml:lang="ru"><p>В статье рассмотрено понятие &amp;laquo;хроническая ишемическая болезнь сердца&amp;raquo;, показаны механизмы ее развития, описывается оценка и лечение ишемической болезни сердца, которая значительно изменилась за последнее десятилетие. Исследуется проблема коморбидности, которая является весьма актуальной в контексте ведения пациентов с ИБС. Рассматриваются европейские рекомендации для коморбидных пациентов с ИБС по лечению и профилактике СС-заболеваний у пациентов с СД, разработанные в сотрудничестве с Европейской ассоциацией по изучению сахарного диабета. Рассмотрена необходимость добавления второго антикоагулянта к АСК для пациентов с острым коронарным синдромом без высокого риска кровотечений для длительной вторичной профилактики. В новых рекомендациях описывается необходимость назначения комбинации НОАК и АСК у пациентов с СД и рецидивирующим заболеванием периферических артерий нижних конечностей при условии отсутствия высокого риска кровотечения. Показана роль антитромботической терапии в лечении больных с хронической ИБС. Показано, кому назначается усиленная антитромботическая терапия при ИБС.</p></abstract><trans-abstract xml:lang="en"><p>The article considers the concept of &amp;laquo;chronic coronary heart disease&amp;raquo;, shows the mechanisms of its development, describes the assessment and treatment of coronary heart disease, which has changed significantly over the past decade. The problem of comorbidity, which is very relevant in the context of the management of patients with coronary heart disease, is investigated. The European recommendations for comorbid patients with coronary heart disease for the treatment and prevention of CV diseases in patients with DM, developed in cooperation with the European Association for the Study of Diabetes Mellitus, are considered. The necessity of adding a second anticoagulant to acetylsalicylic acid for patients with acute coronary syndrome without a high risk of bleeding for long-term secondary prevention is considered. The new recommendations describe the need to prescribe a combination of new oral anticoagulants and acetylsalicylic acid in patients with DM and recurrent peripheral artery disease of the lower extremities, provided there is no high risk of bleeding. The role of antithrombotic therapy in the treatment of patients with chronic coronary heart disease has been shown. It is shown who is prescribed enhanced antithrombotic therapy for coronary heart disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая ишемическая болезнь сердца</kwd><kwd>лечение</kwd><kwd>антитромботическая терапия</kwd><kwd>коморбидные состояния</kwd><kwd>ишемический риск</kwd></kwd-group><kwd-group xml:lang="en"><kwd>сhronic ischemic heart disease</kwd><kwd>treatment</kwd><kwd>antithrombotic therapy</kwd><kwd>comorbid conditions</kwd><kwd>ischemic risk</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Клёсова Е.Ю., Азарова Ю.Э., Суняйкина О.А., Полоников А.В. 2022. Валидация краткого опросника для оценки вклада средовых факторов риска в развитие возраст-зависимых заболеваний на примере сахарного диабета 2 типа и ишемической болезни сердца. 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