Surgical treatment of ventral hernias is still one of the urgent problems of surgery. According to recent studies, ventral hernias are present in 20.9 % of the Russian population. The use of mesh prostheses has increased the percentage of postoperative complications, which is one of the factors that significantly reduce the quality of life of patients. Our goal was to improve the immediate and long-term results of surgical correction of hernias by using DLC-coated PTFE prostheses. For the first time, we evaluated the long-term results of hernioplasty using carbon-coated polytetrafluoroethylene prostheses in patients with abdominal hernias. The clinical part was performed in the conditions of the surgical departments "Belgorod Regional Clinical Hospital of the Prelate Joasaph. The study examined patients who underwent tension-free prosthetic hernioplasty with an inlay prosthesis. As a result of our study, it was found that the quality of life of patients after prosthetic repair of the anterior abdominal wall using a carbon-coated polytetrafluoroethylene prosthesis showed significantly higher total indicators of physical and psychological health. The results obtained indicate that 5 years after the surgical treatment, the patients of the main group show the stability of the restored clinical parameters.