2687-0940Challenges in modern medicine2687-094010.52575/2687-0940-2021-44-2-154-16172INTERNAL DISEASESAnalysis of the intensity of lipid peroxidation in patients with more than 10 years of experience working at nightAnalysis of the intensity of lipid peroxidation in patients with more than 10 years of experience working at nightGribanovIgor A.GribanovIgor A.gribanov_doc@mail.ruZarubinaElena G.ZarubinaElena G.202144200

Fluorescence spectroscopy was performed in 34 male patients with an average age of 40.3 ± 0.9 years in the group with more than 10 years of night work experience. 25 male patients with an average age of 40.2 ± 1.2 years without night work experience were used as controls. The study was carried out using the laser diagnostic complex «LAKK-M» («LAZMA», RF), in the fluorescence mode. In patients working at night for more than 10 years, an increase in the activity of lipid peroxidation (POL) was detected. Such disorders are closely related to the mechanisms of activation of free radical reactions and can cause the development of numerous functional and morphological disorders in organs and tissues. Prolonged night work can lead to increased POL. The nature of the revealed violations of the LPO and the disruption of the antioxidant system of the body against the background of prolonged work at night allows us to assume their significance in the genesis of the development of metabolic disorders at the cellular level.

Fluorescence spectroscopy was performed in 34 male patients with an average age of 40.3 ± 0.9 years in the group with more than 10 years of night work experience. 25 male patients with an average age of 40.2 ± 1.2 years without night work experience were used as controls. The study was carried out using the laser diagnostic complex «LAKK-M» («LAZMA», RF), in the fluorescence mode. In patients working at night for more than 10 years, an increase in the activity of lipid peroxidation (POL) was detected. Such disorders are closely related to the mechanisms of activation of free radical reactions and can cause the development of numerous functional and morphological disorders in organs and tissues. Prolonged night work can lead to increased POL. The nature of the revealed violations of the LPO and the disruption of the antioxidant system of the body against the background of prolonged work at night allows us to assume their significance in the genesis of the development of metabolic disorders at the cellular level.

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