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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Challenges in modern medicine</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2687-0940-2020-43-3-383-391</article-id><article-id pub-id-type="publisher-id">38</article-id><article-categories><subj-group subj-group-type="heading"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Epidemiological features of ventricular rhythm disorders In young post myocardial infarction patients under conditions of ambulatory rehabilitation</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological features of ventricular rhythm disorders In young post myocardial infarction patients under conditions of ambulatory rehabilitation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Novikova</surname><given-names>Irina A.</given-names></name><name xml:lang="en"><surname>Novikova</surname><given-names>Irina A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Nekrutenko</surname><given-names>Ludmila A.</given-names></name><name xml:lang="en"><surname>Nekrutenko</surname><given-names>Ludmila A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Vasilets</surname><given-names>Liubov M.</given-names></name><name xml:lang="en"><surname>Vasilets</surname><given-names>Liubov M.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shishkina</surname><given-names>Ekaterina A.</given-names></name><name xml:lang="en"><surname>Shishkina</surname><given-names>Ekaterina A.</given-names></name></name-alternatives><email>doctor.shishkina@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Rodionov</surname><given-names>Roman A.</given-names></name><name xml:lang="en"><surname>Rodionov</surname><given-names>Roman A.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="epub"><year>2020</year></pub-date><volume>43</volume><issue>3</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2020/3/383-391.pdf" /><abstract xml:lang="ru"><p>Myocardial infarction is the main cause of systolic heart failure. Ventricular arrhythmia is one of the most common causes of sudden cardiac death in such patients. The purpose of the&amp;nbsp;study was to examine the epidemiological features of ventricular arrhythmias in young post myocardial infarction patients at the ambulatory stage of rehabilitation. We examined 108 patients aged 18 to 45 years who experiend myocardial infarction from 01.01.2017 to 01.01.2019. One year after myocardial infarction all patients underwent echocardiography and cardiac rhythm monitoring. According to the echocardiography data 60 % of young patients have diastolic dysfunction, 18 % &amp;ndash; systolic dysfunction, 42 % &amp;ndash; left ventricular asynergy, 16 % &amp;ndash; heart wall aneurysm. In 20 % of cases a maladaptive type of heart remodeling is observed. In young patients at the ambulatory stage of rehabilitation a high average daily heart rate is noted. Frequent premature ventricular contractions are recorded in 30 % of patients and 9,1 % had episodes of ventricular tachycardia. The study results represent negative prognosis in young post myocardial infarction patients.</p></abstract><trans-abstract xml:lang="en"><p>Myocardial infarction is the main cause of systolic heart failure. Ventricular arrhythmia is one of the most common causes of sudden cardiac death in such patients. The purpose of the&amp;nbsp;study was to examine the epidemiological features of ventricular arrhythmias in young post myocardial infarction patients at the ambulatory stage of rehabilitation. We examined 108 patients aged 18 to 45 years who experiend myocardial infarction from 01.01.2017 to 01.01.2019. One year after myocardial infarction all patients underwent echocardiography and cardiac rhythm monitoring. According to the echocardiography data 60 % of young patients have diastolic dysfunction, 18 % &amp;ndash; systolic dysfunction, 42 % &amp;ndash; left ventricular asynergy, 16 % &amp;ndash; heart wall aneurysm. In 20 % of cases a maladaptive type of heart remodeling is observed. In young patients at the ambulatory stage of rehabilitation a high average daily heart rate is noted. Frequent premature ventricular contractions are recorded in 30 % of patients and 9,1 % had episodes of ventricular tachycardia. The study results represent negative prognosis in young post myocardial infarction patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>myocardial infarction</kwd><kwd>young age</kwd><kwd>premature ventricular contractions</kwd><kwd>ventricular tachycardia</kwd><kwd>ambulatory rehabilitation</kwd><kwd>heart remodeling</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>young age</kwd><kwd>premature ventricular contractions</kwd><kwd>ventricular tachycardia</kwd><kwd>ambulatory rehabilitation</kwd><kwd>heart remodeling</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Kovalenko N.V., Chichkova M.A. 2013. Aritmogennaya aktivnost&amp;#39; serdca pri razlichnyh lokalizaciyah Q-infarkta miokarda [The arrhythmogenic activity of the heart in different location of Qmyocardial infarction]. Astrahanskij medicinskij zhurnal, 8 (4): 76&amp;ndash;79.</mixed-citation></ref><ref id="B2"><mixed-citation>Kuznecov V.A., Todosijchuk V.V., Yurkina Yu.A., Lykasova E.A., Nohrina O.Yu., Krinochkin D.V., Kolunin G.V., Gorbatenko E.A., Vizner L.R., Kutrunov V.N., D&amp;#39;yachkov S.M. 2015. Prognozirovanie riska razvitiya zheludochkovyh aritmij vysokih gradacij u pacientov, napravlennyh na koronarnuyu angiografiyu [Prediction of high-grade ventricular arrhythmias in patients referred for the coronary angiography]. Sibirskij medicinskij zhurnal, 30 (1): 105&amp;ndash;111.</mixed-citation></ref><ref id="B3"><mixed-citation>Prakopchik I.V., Gurevich O.V. 2008. Metody opredeleniya neblagopriyatnogo prognoza posle infarkta miokarda [Methods for determining the unfavorable prognosis after myocardial infarction]. Vestnik Smolenskoj gosudarstvennoj medicinskoj akademii, 1: 50&amp;ndash;52.</mixed-citation></ref><ref id="B4"><mixed-citation>Argenziano M.A., Doss M.X., Tabler M., Sachinidis A., Antzelevitch C. 2019. Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis. PLoS One, 14 (5): e0216928.</mixed-citation></ref><ref id="B5"><mixed-citation>Bhar-Amato J., Davies W., Agarwal S. 2017. Ventricular Arrhythmia after Acute Myocardial Infarction: &amp;laquo;The Perfect Storm&amp;raquo;. Arrhythm. Electrophysiol. Rev., 6 (3): 134&amp;ndash;139.</mixed-citation></ref><ref id="B6"><mixed-citation>Biering-Sorensen T., Olsen F.J., Storm K., Fritz-Hansen T., Olsen N.T., Jons C., Vinther M., Sogaard P., Risum N. 2016. Prognostic value of tissue Doppler imaging for predicting ventricular arrhythmias and cardiovascular mortality in ischaemic cardiomyopathy. Eur. Heart. J. Cardiovasc. Imaging, 17 (7): 722&amp;ndash;731.</mixed-citation></ref><ref id="B7"><mixed-citation>Brembilla-Perrot B., Huttin O., Azman B., Sellal J.M., Schwartz J., Olivier A., Blangy H., Sadoul N. 2014. Influence of the mode of management of acute myocardial infarction on the inducibility of ventricular tachyarrhythmias with programmed ventricular stimulation after myocardial infarction. Isr. Med. Assoc. J., 16 (6): 352&amp;ndash;357.</mixed-citation></ref><ref id="B8"><mixed-citation>Chang P.C., Lin S.F., Chu Y., Wo H.T., Lee H.L., Huang Y.C., Wen M.S., Chou C.C. 2019. LCZ696 Therapy Reduces Ventricular Tachyarrhythmia Inducibility in a Myocardial Infarction-Induced Heart Failure Rat Model. Cardiovasc. Ther., 2019.</mixed-citation></ref><ref id="B9"><mixed-citation>D&amp;rsquo;Elia N., D&amp;rsquo;hooge J., Marwick T.H. 2015. Association Between Myocardial Mechanics and Ischemic LV Remodeling. JACC Cardiovasc. Imaging, 8 (12): 1430&amp;ndash;1443.</mixed-citation></ref><ref id="B10"><mixed-citation>Jons C., Sogaard P., Behrens S., Schrader J., Mrosk S., Bloch Thomsen P.E. 2019. The clinical effect of arrhythmia monitoring after myocardial infarction (BIO-GUARD MI): study protocol for a randomized controlled trial. Trials, 20 (1): 563.</mixed-citation></ref><ref id="B11"><mixed-citation>Leon D.G., Lopez-Yunta M., Alfonso-Almaz&amp;aacute;n J.M., Marina-Breysse M., Quintanilla J.G., Sanchez-Gonzalez J., Galan-Arriola C., Castro-Nunez F., Gonzalez-Ferrer J.J., Ibanez B., Perez-Villacastin J., Perez-Castellano N., Fuster V., Jalife J., Vazquez M., Aguado-Sierra J., Filgueiras-Rama D. 2019. Three-dimensional cardiac fibre disorganization as a novel parameter for ventricular arrhythmia stratification after myocardial infarction. Europace, 21 (5): 822&amp;ndash;832.</mixed-citation></ref><ref id="B12"><mixed-citation>Lundblad R., Abdelnoor M., Svennevig J.L. 2004. Surgery for left ventricular aneurysm: early and late survival after simple linear repair and endoventricular patch plast. J. Thorac. Cardiovasc. Surg., 128: 449&amp;ndash;456.</mixed-citation></ref><ref id="B13"><mixed-citation>McMurray J., Kоber L., Robertson M., Dargie H., Colucci W., Lopez-Sendon J., Remme W., Sharpe D.N., Ford I. 2005. Antiarrhythmic effect of carvedilol after acute myocardial infarction: Results of the carvedilol post-infarct survival control in left ventricular dysfunction (CAPRICORN) trial. Journal of the American College of Cardiology, 45 (4): 25&amp;ndash;530.</mixed-citation></ref><ref id="B14"><mixed-citation>Risgaard B., Nielsen J.B., Jabbari R., Haunso S., Holst A.G., Winkel B.G. 2013. Prior myocardial infarction in the young: predisposes to a high relative risk but low absolute risk of a sudden cardiac death. Europace, 15: 48&amp;ndash;54.</mixed-citation></ref><ref id="B15"><mixed-citation>Setoguchi S., Glynn R.J., Avorn J. 2008. Improvements in long-term mortality after myocardial infarction and increased use of cardiovascular drugs after discharge: a 10-year trend analysis. J. Am. Coll. Cardiol., 51: 1247&amp;ndash;1254.</mixed-citation></ref><ref id="B16"><mixed-citation>Solomon S.D., Zelenkofske S., McMurray J.J., Finn P.V., Velazquez E., Ertl G., Harsanyi A., Rouleau J.L., Maggioni A., Kober L., White H., Van de Werf F., Pieper K., Califf R.M., Pfeffer M.A. 2005. Sudden death in patients with myocardial infarction and left ventricular dysfunction, heart failure, or both. N. Engl. J. Med., 352: 2581&amp;ndash;2588.</mixed-citation></ref><ref id="B17"><mixed-citation>St. John Sutton M., Lee D., Rouleau J.L., Goldman S., Plappert T., Braunwald E., Pfeffer M.A. 2003. Left ventricular remodeling and ventricular arrhythmias after myocardial infarction. Circulation, 107 (20): 2577&amp;ndash;2582.</mixed-citation></ref><ref id="B18"><mixed-citation>Tavakoli R., Bettex D., Weber A., Brunner H., Genoni M., Pretre R., Jenni R., Turina M. 2002. Repair of postinfarction dyskinetic LV aneurysm with either linear or patch technique. European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery, 22 (1): 129&amp;ndash;134.</mixed-citation></ref><ref id="B19"><mixed-citation>Tomaselli G.F., Zipes D.P. 2004. What causes sudden death in heart failure? Circ Res, 95: 754&amp;ndash;763.</mixed-citation></ref><ref id="B20"><mixed-citation>World Health Organization. The top 10 causes of death. 2014. Available: http://www.who.int/mediacentre/factsheets/fs310/en/.</mixed-citation></ref></ref-list></back></article>