The aim of the work is to improve the results of treatment of chronic generalized periodontitis by recovery of cytokines with the use of VHF therapy and immunomodulator. 240 people were recruited to conduct the study. The study program consisted of including several groups of patients. The first group consisted of 80 patients diagnosed with HCP who received traditional treatment. In the second group 80 patients were included, to whom the usual therapy was supplemented by the use of VHF therapy, the third group consisted of 80 people, the treatment of which in addition to the usual therapy was supplemented by the introduction of an immunomodulator – polyoxidonium, which was used per os, 1 tablet 2 times a day 30 minutes before meals for 10 days, at the same time a session of BHF therapy was carried out. The patients of the other two clinical groups, as pathogenetic therapy, which was aimed at improving immune status and early reduction of signs of inflammation in periodontal tissue, were used KVF therapy. As a result of the study, it was found that the separate use of VHF therapy and immunomodulators in the treatment of chronic generalized light and moderate periodontitis does not lead to a faster recovery of blood serum interlexins. For faster reduction of interlexins in blood serum it is necessary to simultaneously use VHF therapy and immunomodulator. As immunomodulator it is recommended to use polyoxidonium in tablet form, 20–30 minutes before meals, every day 2 times a day, seven days.
The aim of the work is to improve the results of treatment of chronic generalized periodontitis by recovery of cytokines with the use of VHF therapy and immunomodulator. 240 people were recruited to conduct the study. The study program consisted of including several groups of patients. The first group consisted of 80 patients diagnosed with HCP who received traditional treatment. In the second group 80 patients were included, to whom the usual therapy was supplemented by the use of VHF therapy, the third group consisted of 80 people, the treatment of which in addition to the usual therapy was supplemented by the introduction of an immunomodulator – polyoxidonium, which was used per os, 1 tablet 2 times a day 30 minutes before meals for 10 days, at the same time a session of BHF therapy was carried out. The patients of the other two clinical groups, as pathogenetic therapy, which was aimed at improving immune status and early reduction of signs of inflammation in periodontal tissue, were used KVF therapy. As a result of the study, it was found that the separate use of VHF therapy and immunomodulators in the treatment of chronic generalized light and moderate periodontitis does not lead to a faster recovery of blood serum interlexins. For faster reduction of interlexins in blood serum it is necessary to simultaneously use VHF therapy and immunomodulator. As immunomodulator it is recommended to use polyoxidonium in tablet form, 20–30 minutes before meals, every day 2 times a day, seven days.