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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Challenges in modern medicine</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.52575/2687-0940-2026-49-1-86-97</article-id><article-id pub-id-type="publisher-id">280</article-id><article-categories><subj-group subj-group-type="heading"><subject>STOMATOLOGY</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;Investigation of Naswar Effect on the Condition of the Oral Cavity and its Role in the Development of General Somatic Pathology. Analysis of Existing Data&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;Investigation of Naswar Effect on the Condition of the Oral Cavity and its Role in the Development of General Somatic Pathology. Analysis of Existing Data&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shaiakhmetova</surname><given-names>Kanyshai D.</given-names></name><name xml:lang="en"><surname>Shaiakhmetova</surname><given-names>Kanyshai D.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Kuttubaeva</surname><given-names>Klara B.</given-names></name><name xml:lang="en"><surname>Kuttubaeva</surname><given-names>Klara B.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Simionidi</surname><given-names>Yefimiya K.</given-names></name><name xml:lang="en"><surname>Simionidi</surname><given-names>Yefimiya K.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="epub"><year>2026</year></pub-date><volume>49</volume><issue>1</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2026/1/АПМ_2026_Том_49__1_86-97.pdf" /><abstract xml:lang="ru"><p>The purpose of this review is to analyze scientific data on the effects of naswar on oral health, to study the mechanisms of its influence on the body and reveal the socio-cultural factors contributing to its consumption. The materials and research methods included a systematic search for literature in the databases PubMed, eLibrary and Google Scholar using keywords. Relevant publications from 2015 to 2025 were selected, including original articles, reviews, and meta-analyses. The review examines current research on the effects of naswai on oral health and the body as a whole, highlighting the key mechanisms of its negative impact. A direct correlation has been established between the use of this product and an increased risk of developing general somatic diseases, precancerous changes and oncopathologies of the oropharyngeal region. A promising area of further research is to study the long-term effects of naswar consumption, as well as to develop effective prevention strategies and reduce harm to public health.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of this review is to analyze scientific data on the effects of naswar on oral health, to study the mechanisms of its influence on the body and reveal the socio-cultural factors contributing to its consumption. The materials and research methods included a systematic search for literature in the databases PubMed, eLibrary and Google Scholar using keywords. Relevant publications from 2015 to 2025 were selected, including original articles, reviews, and meta-analyses. The review examines current research on the effects of naswai on oral health and the body as a whole, highlighting the key mechanisms of its negative impact. A direct correlation has been established between the use of this product and an increased risk of developing general somatic diseases, precancerous changes and oncopathologies of the oropharyngeal region. A promising area of further research is to study the long-term effects of naswar consumption, as well as to develop effective prevention strategies and reduce harm to public health.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>nasvay</kwd><kwd>naswar</kwd><kwd>smokeless tobacco</kwd><kwd>nicotine</kwd><kwd>oral cancer</kwd><kwd>general somatic pathology</kwd><kwd>oral microbiota</kwd><kwd>leukoplakia</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nasvay</kwd><kwd>naswar</kwd><kwd>smokeless tobacco</kwd><kwd>nicotine</kwd><kwd>oral cancer</kwd><kwd>general somatic pathology</kwd><kwd>oral microbiota</kwd><kwd>leukoplakia</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Bogatyreva M.M., Kakeev B.A. 2021. 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