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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Challenges in modern medicine</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.52575/2687-0940-2026-49-1-16-25</article-id><article-id pub-id-type="publisher-id">274</article-id><article-categories><subj-group subj-group-type="heading"><subject>INTERNAL DISEASES</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;Predictors of Adverse Outcomes of Traumatic Brain Injury&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;Predictors of Adverse Outcomes of Traumatic Brain Injury&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Yakunchenko</surname><given-names>Tatiana I.</given-names></name><name xml:lang="en"><surname>Yakunchenko</surname><given-names>Tatiana I.</given-names></name></name-alternatives><email>yakunchenko@bsuedu.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Lysenko</surname><given-names>Anastasia S.</given-names></name><name xml:lang="en"><surname>Lysenko</surname><given-names>Anastasia S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Pyatakovich</surname><given-names>Felix Pyatakovich</given-names></name><name xml:lang="en"><surname>Pyatakovich</surname><given-names>Felix Pyatakovich</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Gontarev</surname><given-names>Sergey N.</given-names></name><name xml:lang="en"><surname>Gontarev</surname><given-names>Sergey N.</given-names></name></name-alternatives><email>znamisng@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Bakhareva</surname><given-names>Arina A.</given-names></name><name xml:lang="en"><surname>Bakhareva</surname><given-names>Arina A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shmarova</surname><given-names>Diana R.</given-names></name><name xml:lang="en"><surname>Shmarova</surname><given-names>Diana R.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Fedoseev</surname><given-names>Ilya M.</given-names></name><name xml:lang="en"><surname>Fedoseev</surname><given-names>Ilya M.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shorokhova</surname><given-names>Anastasia A.</given-names></name><name xml:lang="en"><surname>Shorokhova</surname><given-names>Anastasia A.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="epub"><year>2026</year></pub-date><volume>49</volume><issue>1</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2026/1/АПМ_2026_Том_49__1_16-25.pdf" /><abstract xml:lang="ru"><p>The aim of the study is to identify prognostic predictors of adverse outcomes of moderate traumatic brain injury (TBI). The study included 199 patients with adverse outcomes of TBI. Patient complaints and information about concomitant diseases were retrospectively copied. The evaluation of the prognostic significance of complaints and concomitant diseases was performed according to the calculated values of&amp;nbsp;the odds ratio. Our findings show that among the complaints, complaints of vomiting, nausea and excessive&amp;nbsp;fatigue have the greatest predictive ability with reliable odds ratios of 3.452, 3.239 and 3.102. Among the studied concomitant diseases, it is proposed to use the presence of chronic heart failure and&amp;nbsp;coronary heart disease in the patient to predict adverse outcomes of moderate TBI. The presence of&amp;nbsp;these predictors allows attributing patients to the risk group for the development of adverse outcomes of&amp;nbsp;moderate TBI.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study is to identify prognostic predictors of adverse outcomes of moderate traumatic brain injury (TBI). The study included 199 patients with adverse outcomes of TBI. Patient complaints and information about concomitant diseases were retrospectively copied. The evaluation of the prognostic significance of complaints and concomitant diseases was performed according to the calculated values of&amp;nbsp;the odds ratio. Our findings show that among the complaints, complaints of vomiting, nausea and excessive&amp;nbsp;fatigue have the greatest predictive ability with reliable odds ratios of 3.452, 3.239 and 3.102. Among the studied concomitant diseases, it is proposed to use the presence of chronic heart failure and&amp;nbsp;coronary heart disease in the patient to predict adverse outcomes of moderate TBI. The presence of&amp;nbsp;these predictors allows attributing patients to the risk group for the development of adverse outcomes of&amp;nbsp;moderate TBI.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>traumatic brain injury</kwd><kwd>prognosis</kwd><kwd>adverse outcomes</kwd><kwd>predictors of adverse outcomes</kwd><kwd>complaints</kwd><kwd>concomitant diseases</kwd></kwd-group><kwd-group xml:lang="en"><kwd>traumatic brain injury</kwd><kwd>prognosis</kwd><kwd>adverse outcomes</kwd><kwd>predictors of adverse outcomes</kwd><kwd>complaints</kwd><kwd>concomitant diseases</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Potapov A.A., Krylov V.V., Petrikov A.S. 2024. 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