This article is devoted to the study of the effect of influenza infection on periodontal tissues and the features of rehabilitation of patients with oral diseases in conditions of viral activity. Influenza, causing significant changes in the immune system, leads to deterioration of periodontal tissues and increases vulnerability to infectious processes. The article analyzes modern protocols of dental practice, including drug treatment, physiotherapy methods, the use of herbal preparations and technologies such as ozone therapy and the Vector system. Particular attention is paid to the correction of home oral hygiene and psycho-emotional support of patients, which is an important aspect of comprehensive rehabilitation. The results of the study emphasize the need for an integrative approach to rehabilitation, which can significantly accelerate recovery and reduce the risk of chronic periodontal diseases.