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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Challenges in modern medicine</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.52575/2687-0940-2025-48-1-29-36</article-id><article-id pub-id-type="publisher-id">227</article-id><article-categories><subj-group subj-group-type="heading"><subject>STOMATOLOGY</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;Periodontal Disease and Mineral Composition of Saliva among Adolescents in the Nenets Autonomous District&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;Periodontal Disease and Mineral Composition of Saliva among Adolescents in the Nenets Autonomous District&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Gorbatova</surname><given-names>Maria A.</given-names></name><name xml:lang="en"><surname>Gorbatova</surname><given-names>Maria A.</given-names></name></name-alternatives><email>marigora@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Algazina</surname><given-names>Aleksandra A.</given-names></name><name xml:lang="en"><surname>Algazina</surname><given-names>Aleksandra A.</given-names></name></name-alternatives><email>algazina.sascha@ya.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Utkina</surname><given-names>Elena I.</given-names></name><name xml:lang="en"><surname>Utkina</surname><given-names>Elena I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Pechinkina</surname><given-names>Natalia I.</given-names></name><name xml:lang="en"><surname>Pechinkina</surname><given-names>Natalia I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Grjibovski</surname><given-names>Andrey M.</given-names></name><name xml:lang="en"><surname>Grjibovski</surname><given-names>Andrey M.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="epub"><year>2025</year></pub-date><volume>48</volume><issue>1</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2025/1/АПМ_т.48_1_2025_29-36.pdf" /><abstract xml:lang="ru"><p>Periodontal diseases are among the most common dental pathologies in the world. Studying the composition of saliva can help with early diagnosis of periodontal diseases. Aim: To study associations between periodontal disease (PD) and mineral composition of saliva among adolescents in the Arctic. A total of 171 15&amp;ndash;17-year-old adolescents participated in a cross-sectional study&amp;nbsp; based on the method-ology of the World Health Organization. Prevalence ratios (PR) were used as measures of association. Higher concentration of Na was associated with bleeding (OR = 2.01, p = 0.053). Higher Mg content in saliva was significantly associated with fewer sextants with bleeding (PR = 0.39, p = 0.041), calculus (OR = 0.46, p&amp;nbsp;=&amp;nbsp;0.005) and with PD (OR = 0.46, p = 0.001). The high amount of P was significantly associated with more sextants with calculus (OR = 2.16, p = 0.013). Saliva ionomics is currently gain-ing an increasing importance due to its simple implementation, non-invasiveness and significant poten-tial for early diagnosis and prediction of the course of PD among adolescents.</p></abstract><trans-abstract xml:lang="en"><p>Periodontal diseases are among the most common dental pathologies in the world. Studying the composition of saliva can help with early diagnosis of periodontal diseases. Aim: To study associations between periodontal disease (PD) and mineral composition of saliva among adolescents in the Arctic. A total of 171 15&amp;ndash;17-year-old adolescents participated in a cross-sectional study&amp;nbsp; based on the method-ology of the World Health Organization. Prevalence ratios (PR) were used as measures of association. Higher concentration of Na was associated with bleeding (OR = 2.01, p = 0.053). Higher Mg content in saliva was significantly associated with fewer sextants with bleeding (PR = 0.39, p = 0.041), calculus (OR = 0.46, p&amp;nbsp;=&amp;nbsp;0.005) and with PD (OR = 0.46, p = 0.001). The high amount of P was significantly associated with more sextants with calculus (OR = 2.16, p = 0.013). Saliva ionomics is currently gain-ing an increasing importance due to its simple implementation, non-invasiveness and significant poten-tial for early diagnosis and prediction of the course of PD among adolescents.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>periodontal disease</kwd><kwd>mineral composition of saliva</kwd><kwd>adolescents</kwd><kwd>Arctic</kwd><kwd>Nenets Autonomous district</kwd></kwd-group><kwd-group xml:lang="en"><kwd>periodontal disease</kwd><kwd>mineral composition of saliva</kwd><kwd>adolescents</kwd><kwd>Arctic</kwd><kwd>Nenets Autonomous district</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Matveeva E.V., Antonova I.N., Kipchuk A.V. 2023. The Effect of Comorbidities on Periodontal and Hygiene Indices, and Oral Fluid Mineral Composition. 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