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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Challenges in modern medicine</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.52575/2687-0940-2024-47-3-418-434</article-id><article-id pub-id-type="publisher-id">215</article-id><article-categories><subj-group subj-group-type="heading"><subject>SURGERY</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;Development of a Prognostic Mathematical Model for Traumatic Liver Damage&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;Development of a Prognostic Mathematical Model for Traumatic Liver Damage&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Vorontsov</surname><given-names>Aleksey K.</given-names></name><name xml:lang="en"><surname>Vorontsov</surname><given-names>Aleksey K.</given-names></name></name-alternatives><email>ale92112855@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Olshevskiy</surname><given-names>Aleksandr A.</given-names></name><name xml:lang="en"><surname>Olshevskiy</surname><given-names>Aleksandr A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Korsakov</surname><given-names>Anton V.</given-names></name><name xml:lang="en"><surname>Korsakov</surname><given-names>Anton V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Parkhisenkо</surname><given-names>Yury A.</given-names></name><name xml:lang="en"><surname>Parkhisenkо</surname><given-names>Yury A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Bezaltynnykh</surname><given-names>Alexander A.</given-names></name><name xml:lang="en"><surname>Bezaltynnykh</surname><given-names>Alexander A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Sukharukov</surname><given-names>Alexander S.</given-names></name><name xml:lang="en"><surname>Sukharukov</surname><given-names>Alexander S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Cherednikov</surname><given-names>Evgeniy F.</given-names></name><name xml:lang="en"><surname>Cherednikov</surname><given-names>Evgeniy F.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Troshin</surname><given-names>Vladislav P.</given-names></name><name xml:lang="en"><surname>Troshin</surname><given-names>Vladislav P.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Barannikov</surname><given-names>Sergey V.</given-names></name><name xml:lang="en"><surname>Barannikov</surname><given-names>Sergey V.</given-names></name></name-alternatives><email>svbarannikov@rambler.ru</email></contrib></contrib-group><pub-date pub-type="epub"><year>2024</year></pub-date><volume>47</volume><issue>3</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2024/3/АПМ_2024_418-434_eHHJPCN.pdf" /><abstract xml:lang="ru"><p>Intra-abdominal bleeding is a leading cause of adverse outcomes in liver trauma, underscoring the critical importance of timely surgical intervention and optimal hemostasis strategies. This study investigates the impact of liver model segmentation on the distribution of mechanical stresses during impact simulation using the finite element method. By discretizing a computer-aided design (CAD) model into finite elements of two types &amp;ndash; 4-node linear isoparametric elements for the parenchyma and 3-node Kirchhoff plate elements for intersegmental partitions &amp;ndash; we developed a computational liver model adequately captures the organ&amp;#39;s anatomy. Our results show that incorporating segmentation significantly affects the simulation outcomes, enabling a more realistic assessment of tissue damage patterns upon impact. This approach facilitates the simulation of a wide range of real-world traumatic effects, allowing for arbitrary specification of impact direction, speed, and affected area. By accounting for liver segmentation, our study provides a more accurate and comprehensive understanding of traumatic liver injuries, ultimately informing clinical decision-making and improving patient outcomes.</p></abstract><trans-abstract xml:lang="en"><p>Intra-abdominal bleeding is a leading cause of adverse outcomes in liver trauma, underscoring the critical importance of timely surgical intervention and optimal hemostasis strategies. This study investigates the impact of liver model segmentation on the distribution of mechanical stresses during impact simulation using the finite element method. By discretizing a computer-aided design (CAD) model into finite elements of two types &amp;ndash; 4-node linear isoparametric elements for the parenchyma and 3-node Kirchhoff plate elements for intersegmental partitions &amp;ndash; we developed a computational liver model adequately captures the organ&amp;#39;s anatomy. Our results show that incorporating segmentation significantly affects the simulation outcomes, enabling a more realistic assessment of tissue damage patterns upon impact. This approach facilitates the simulation of a wide range of real-world traumatic effects, allowing for arbitrary specification of impact direction, speed, and affected area. By accounting for liver segmentation, our study provides a more accurate and comprehensive understanding of traumatic liver injuries, ultimately informing clinical decision-making and improving patient outcomes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>liver</kwd><kwd>sectoral system</kwd><kwd>numerical modeling</kwd><kwd>finite element method</kwd><kwd>impact simulation</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver</kwd><kwd>sectoral system</kwd><kwd>numerical modeling</kwd><kwd>finite element method</kwd><kwd>impact simulation</kwd></kwd-group></article-meta></front><back><ack><p>The authors express their deep gratitude to Alexey Andreevich Olshevsky, Candidate of Technical Sciences, Associate Professor, for his help in preparing the model and performing calculations.

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