Currently, in Russia, as well as throughout the world, there is a tendency towards an increase in the incidence and prevalence of gastroesophageal reflux disease. This condition is characterized by a significant decrease in the quality of life of patients and the frequent development of relapses. At the same time, the majority of patients, due to the delay in making the correct diagnosis and low compliance with therapy, receive inadequate treatment. Often patients do not take the most effective drugs or do not adhere to the timing of treatment. The vast majority of patients with GERD are patients at clinics. Moreover, due to the lack of time on an outpatient basis, insufficient attention is paid to such patients. Based on the foregoing, it is necessary to continue research aimed at finding the most optimal ways to treat GERD and ways to increase compliance. This paper discusses the features of the clinic and diagnosis of GERD at the outpatient stage among the population of the Oryol region, analyzes the treatment results of such patients with an assessment of their quality of life.