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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Challenges in modern medicine</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2687-0940-2020-43-1-5-15</article-id><article-id pub-id-type="publisher-id">2</article-id><article-categories><subj-group subj-group-type="heading"><subject>INTERNAL DISEASES</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;LASER THERAPY IN CHRONIC VIRAL HEPATITIS TREATMENT&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;LASER THERAPY IN CHRONIC VIRAL HEPATITIS TREATMENT&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Burduli</surname><given-names>N. M.</given-names></name><name xml:lang="en"><surname>Burduli</surname><given-names>N. M.</given-names></name></name-alternatives><email>burduli@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Krifaridi,</surname><given-names>A. S.</given-names></name><name xml:lang="en"><surname>Krifaridi,</surname><given-names>A. S.</given-names></name></name-alternatives><email>anastasya.krifaridi@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Aksenova</surname><given-names>I. Z.</given-names></name><name xml:lang="en"><surname>Aksenova</surname><given-names>I. Z.</given-names></name></name-alternatives><email>crocon@mail.ru</email></contrib></contrib-group><pub-date pub-type="epub"><year>2020</year></pub-date><volume>43</volume><issue>1</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2020/1/5-15.pdf" /><abstract xml:lang="ru"><p>The aim of the work was to study the effect of low-intensity laser radiation on the vascular endotheliumtotal oxide metabolites, and the state of capillary blood flow. The patients participating in the study were divided into three groups: in the first (control) group (30 people), only traditional drug therapy was used for treatment, patients of the second group (the main group, 85 people) received a course of intravenous laser therapy along with medication, and the third group of patients (the main group, 45 people) received a course of cutaneous laser therapy. The results of our study show that drug therapy of patients with chronic viral hepatitis is not accompanied by credible improvements to the content in blood plasma nitric oxide metabolites, and indicators of microcirculation, and the inclusion in the complex treatment of laser therapy provides statistically significant performance improvement in capillary blood flow and dysfunction of vascular endothelium.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the work was to study the effect of low-intensity laser radiation on the vascular endotheliumtotal oxide metabolites, and the state of capillary blood flow. The patients participating in the study were divided into three groups: in the first (control) group (30 people), only traditional drug therapy was used for treatment, patients of the second group (the main group, 85 people) received a course of intravenous laser therapy along with medication, and the third group of patients (the main group, 45 people) received a course of cutaneous laser therapy. The results of our study show that drug therapy of patients with chronic viral hepatitis is not accompanied by credible improvements to the content in blood plasma nitric oxide metabolites, and indicators of microcirculation, and the inclusion in the complex treatment of laser therapy provides statistically significant performance improvement in capillary blood flow and dysfunction of vascular endothelium.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>endothelial dysfunction</kwd><kwd>microcirculation</kwd><kwd>nitric oxide</kwd><kwd>chronic hepatitis</kwd><kwd>low-intensity laser therapy</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endothelial dysfunction</kwd><kwd>microcirculation</kwd><kwd>nitric oxide</kwd><kwd>chronic hepatitis</kwd><kwd>low-intensity laser therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>1. Abakumov M.M., Golikov P.P. 2005. 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