Список литературы

2687-0940

Challenges in modern medicine

2687-0940

10.52575/2687-0940-2024-47-1-89-98

186

STOMATOLOGY

<strong>Microbial Composition of the Periodontal Pocket in Chronic Generalized Periodontitis</strong>

Yashnova

Nadezhda B.

Yashnova

Nadezhda B.

nadezhday1990@yandex.ru

Pinelis

Yuri I.

Pinelis

Yuri I.

Dutova

Anastasia A.

Dutova

Anastasia A.

2024

47100

The aim of the study was to evaluate the microbiocenosis of the periodontal pocket in chronic generalized periodontitis. Materials: The study included 106 patients with chronic generalized paradontitis of varying severity who were on an outpatient appointment with a dentist-surgeon. Methods: the study was performed by PCR method with real-time detection of the results, on the DT-96 detecting amplifier of NPO DNA Technology LLC Periodontoscreen kit. Statistical processing of the obtained results was carried out using the SPSS Statistics 11.0 program. Results: Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythensis, Treponema denticola were found in etiologically significant concentrations in patients with chronic generalized periodontitis. At the same time, Porphyromonas gingivalis, Treponema denticola and Tannerella forsythensis were most often verified in patients, Prevotella intermedia was detected in a smaller number. Given this fact, it remains relevant to study the identified microorganisms in patients with chronic generalized paradontitis in order to establish their role in the etiopathogenesis of this disease.

chronic periodontitisPorphyromonas gingivalisPrevotella intermediaTannerella forsythensisTreponema denticolapolymerase chain reaction (PCR) method

The work was carried out without external sources of funding.

Список литературы

Atrushkevich V.G., Tihomirova E.A., Zudina I.V. 2018. Osobennosti mikrobiocenoza zubnogo naleta u pacientov s agressivnym i hronicheskim generalizovannym parodontitom [Features of Dental Plaque Microbiocenosis in Patients with Aggressive and Chronic Generalized Periodontitis]. Kremlevskaya medicina. Klinicheskij vestnik [Kremlin medicine. Clinical Journal]. 2: 88–97.

Bazhutova I.V., Ismatulin D.D., Lyamin A.V., Trunin D.A., Zhestkov A.V., Razumnyj V.A. 2022. Klinicheskoe znachenie predstavitelej roda Streptococcus pri razvitii parodontita [Clinical Significance of Members of the Genus Streptococcus in the Development of Periodontitis]. Infekciya i immunitet [Infection and Immunity]. 12(1): 51–58. doi: 10.15789/2220-7619-CSO-1698

Bazarnyj V.V., Polushina L.G., Maksimova A.Y., Svetlakova E.N., Mandra Y.V. 2018. Patogeneticheskoe obosnovanie novyh podhodov k ocenke sostoyaniya tkanej polosti rta pri hronicheskom generalizovannom parodontite [Pathogenetic Rationale for New Approaches to Assessing the Condition of Oral Tissues in Chronic Generalized Periodontitis]. Problemy stomatologii [Problems in Dentistry]. 14(4): 14–18. doi: 10.18481/2077-7566-2018-14-4-14-18

Bazarnyj V.V., Polushina L.G., Maksimova A.Y., Svetlakova E.N., Mandra Y.V. 2018. Citologicheskaya harakteristika bukkal'nogo epiteliya pri hronicheskom generalizovannom parodontite [Cytological Characteristics of the Buccal Epithelium in Chronic Generalized Periodontitis]. Klinicheskaya laboratornaya diagnostika [Clinical Laboratory Diagnostics]. 63(12): 773–776. doi: 10.18821/0869-2084-2018-63-12-773-776

Bulgakova A.I., Mavzyutov A.R, Tamarova E.R., Vasil'eva N.A., Shvec K.Y. 2017. Kliniko-mikrobiologicheskoe obosnovanie kompleksnogo lecheniya bol'nyh parodontitom so srednej i tyazheloj stepen'yu tyazhesti s uchetom molekulyarno-geneticheskoj harakteristiki mikrobioty polosti rta [Clinical and Microbiological Substantiation of Complex Treatment of Patients with Periodontitis with Moderate and Severe Severity, Taking into Account with Consideration to the Molecular Genetic Characteristics of the Oral Microbiota]. Parodontologiya [Periodontology]. 1(82): 70–74.

Galieva A.S., Davidovich N.V., Opravin A.S, Bazhukova T.A., Shagrov L.L., Bashilova E.N., Gagarina T.Yu. 2022. Endoekologiya polosti rta i citomorfologicheskie osobennosti bukkal'nogo epiteliya u lic s vospalitel'nymi zabolevaniyami parodonta [Endoecology of the Oral Cavity and Cytomorphological Features of the Buccal Epithelium in Individuals with Inflammatory Periodontal Diseases]. Ekologiya cheloveka [Human ecology]. 29(7): 471–480. doi: 10.17816/humeco106242

Gerasimova L.P., Usmanova I.N., Usmanov I.R., Husnarizanova R.F., Al'-Kofish M.A.M. 2017. Osobennosti sostoyaniya stomatologicheskogo i mikrobiologicheskogo statusa polosti rta u lic s vospalitel'nymi zabolevaniyami parodonta v zavisimosti ot vozrasta [Features of the Dental and Microbiological Status of the Oral Cavity in Persons with Inflammatory Periodontal Diseases Depending on Age]. Ural'skij medicinskij zhurnal [Ural Medical Journal]. 7: 5–9.

Gerasimova L.P., Hajbullina R.R., Kabirova M.F., Usmanova I.N., Karimova S.R. 2017. Mikrobiologicheskaya ocenka sostoyaniya polosti rta u pacientov s hronicheskimi vospalitel'nymi zabolevaniyami parodonta [Microbiological Assessment of the Oral Cavity in Patients with Chronic Inflammatory Periodontal Diseases]. Ural'skij Medicinskij zhurnal seriya Stomatologiya [Ural Medical Journal Dentistry series]. 7: 42–45.

Gerasimova L.P., Hajbullina R.R., Kuznecova L.I., Astahova M.I., Shamsiev M.R., Gubajdullin I.R., Kuleshova T.P., Tayupova I.M. 2017. Sostoyanie mikroflory polosti rta u pacientov s hronicheskimi vospalitel'nymi zabolevaniyami parodonta [The State of the Oral Microflora in Patients with Chronic Inflammatory Periodontal Diseases]. Aspirantskij vestnik Povolzh'ya [Postgraduate Bulletin of the Volga region]. 5–6: 87–92.

Gorbacheva I.A., Orehova L.Yu., Sycheva Yu.A., Chudinova T.N., Mihajlova O.V. 2018. Faktory vzaimnogo otyagoscheniya mnozhestvennyh hronicheskih ochagov infekcii i generalizovannogo parodontita [Factors of Mutual Aggravation of Multiple Chronic Foci of Infection and Generalized Periodontitis]. Uchenye zapiski SPbGMU im. akad. I.P. Pavlova [Scientific Notes of Academician I.P. Pavlov St. Petersburg State Medical University]. 25(1): 50–55.

Gordeev A.V., Galushko E.A., Savushkina N.M., Lila A.M. 2018. Parodontit – predvestnik revmatoidnogo artrita? [Is Periodontitis a Precursor to Rheumatoid Arthritis?] Nauchno-prakticheskaya revmatologiya [Scientific and Practical Rheumatology]. 56(5): 613–620.

Grigoryan V.A., Perikova M.G., Sirak S.V., Schetinin E.V., Dolgalev A.A., Bobryshev D.V., Remizova A.A., Dzgoeva M.G. 2019. Osobennosti klinicheskogo vybora antibakterial'nyh sredstv terapii hronicheskogo generalizovannogo parodontita po rezul'tatam mikrobiologicheskogo i molekulyarno-geneticheskogo issledovaniya [Features of the Clinical Choice of Antibacterial Agents for the Treatment of Chronic Generalized Periodontitis Based on the Results of Microbiological and Molecular Genetic Studies]. Medicinskij vestnik Severnogo Kavkaza [Medical Bulletin of the North Caucasus]. 14(4): 649–653. doi: 10.14300/mnnc.2019.14161

Leonov G.E., Varaeva Yu.R., Livancova E.N., Starodubova A.V. 2023. Osobennosti mikrobioma rotovoj polosti pri razlichnyh somaticheskih zabolevaniyah [Features of the Oral Microbiome in Various Somatic Diseases]. Voprosy pitaniya [Nutrition Issues]. 92(4): 6–19. doi: 10.33029/0042-8833-2023-92-4-6-19

Maslyakov V.V., Pronina E.A., Abakumova Yu.V., Il'yuhin A.V. 2018. Korrekciya mikroflory soderzhimogo parodontal'nogo karmana pacientov s hronicheskim generalizovannym parodontitom pri pomoschi KVCh-terapii [Correction of the Microflora of the Contents of the Periodontal Pocket of Patients with Chronic Generalized Periodontitis Using EHF Therapy]. Zhurn. med.-biol. Issledovanij [Journal med.-biol. Research]. 6(1): 67–76. doi: 10.17238/issn2542-1298.2018.6.1.67

Miklyaev S.V., Leonova O.M., Suschenko A.V. 2018. Analiz rasprostranennosti hronicheskih vospalitel'nyh zabolevanij tkanej parodonta [Analysis of the Prevalence of Chronic Inflammatory Diseases of Periodontal Tissues]. Elektronnaya kniga [E-book]. URL: https://science-education.ru/ru/article/view?id=27454 (accessed: 02.09.2023).

Nesterov A.M., Hajkin M.B., Chigarina S.E., Sadykov M.I., Sagirov M.R. 2020. Izuchenie kachestva zhizni u pacientov s zabolevaniem parodonta [Study of the Quality of Life in Patients with Periodontal Disease]. Innovacionnyj potencial razvitiya nauki v sovremennom mire: dostizheniya i innovacii. Materialy IV Mezhdunarodnoj nauchno-prakticheskoj konferencii (UFA, 2 oktyabrya 2020 g.). Ufa, Izd-vo «Vestnik nauki» [Innovative Potential of Science Development in the Modern World: Achievements and Innovations. Materials of the IV International Scientific and Practical Conference (UFA, October 2, 2020). Ufa, Bulletin of Science Publishing House]. 109–113.

Orehova L.Y., Loboda E.S., Yamanidze N.A. 2018. Sovershenstvovanie metodov diagnostiki i lecheniya vospalitel'nyh zabolevanij parodonta s ispol'zovaniem razlichnyh form preparatov ozona putem ocenki mikrocirkulyacii tkanej parodonta [Improving the Methods of Diagnosis and Treatment of Inflammatory Periodontal Diseases Using Various Forms of Ozone Preparations by Assessing the Microcirculation of Periodontal Tissues]. Parodontologiya [Periodontics]. 23,1(86): 58–63.

Tamarova E.R., Shvec K.Yu., Mavzyutov A.R., Bajmiev A.H., Bulgakova A.I. 2020. Sozdanie molekulyarno-geneticheskoj test-sistemy dlya rannej diagnostiki i ocenki effektivnosti lecheniya vospalitel'nyh zabolevanij parodonta [Creation of a Molecular Genetic Test System for Early Diagnosis and Evaluation of the Effectiveness of Treatment of Inflammatory Periodontal Diseases]. Klinicheskaya laboratornaya diagnostika [Clinical Laboratory Diagnostics]. 65(1): 55–60. doi: 10.18821/0869-2084-2020-65-1-55-60

Tarasenko S.V., Katola V.M., Komogorceva V.E. 2018. Vliyanie mikrobioty polosti rta na razvitie vospaleniya i somaticheskih zabolevanij [The Influence of Oral Microbiota on the Development of Inflammation and Somatic Diseases]. Rossijskij stomatologicheskij zhurnal [Russian Dental Journal]. 22(3): 162–165. doi: 10.18821/1728-2802-2018-22-3-162-165

Carev V.N., Nikolaeva E.N., Ippolitov E.V. 2017. Parodontopatogennye bakterii – osnovnoj faktor vozniknoveniya i razvitiya parodontita [Periodontal Pathogenic Bacteria are the Main Factor in the Occurrence and Development of Periodontitis]. Zhurn. Mikrobiol [Journal of Microbiology]. 5: 101–112.