To identify the relationship between global longitudinal deformation of the left ventricle and the state of the coronary bed in patients with stable exertional angina, the study included 63 male patients with coronary heart disease: stable exertional angina and preserved systolic function of the left ventricle (left ventricular ejection fraction of more than 50 % (Simpson method)). At the time of the study, all patients were in sinus rhythm. Coronary angiography was performed using the Siemens Artis Zee (Germany) unit according to the standard technique. Echocardiography was performed 1 day before coronary angiography using a Philips EPIQ 7 device (USA) according to the standard method, in addition, the global longitudinal strain of the left ventricle was assessed using speckle tracking technology. The study showed that the index of global longitudinal deformation of the left ventricle in the group of patients (39 people) with severe lesions of the coronary arteries (stenosis ≥ 71 %). was statistically significantly lower than in the group of patients (24 people) with moderate atherosclerotic lesions of the coronary arteries (stenosis 21–70 %) (p = 0,016), -15,3 [-11,3; -17,7] % and -19,2 [-16,1; -23,6] %, respectively. In patients with stable exertional angina, if a global longitudinal strain of the left ventricle is detected below -16,4 % according to speckle tracking echocardiography, the risk of identifying significant coronary artery disease (stenosis ≥ 71%) is very high.