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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2687-0940</journal-id><journal-title-group><journal-title>Challenges in modern medicine</journal-title></journal-title-group><issn pub-type="epub">2687-0940</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2687-0940-2020-43-1-135-145</article-id><article-id pub-id-type="publisher-id">16</article-id><article-categories><subj-group subj-group-type="heading"><subject>SURGERY</subject></subj-group></article-categories><title-group><article-title>THE TISSUE PATHOMORPHOSIS AROUND THE MESH REPEREN&amp;reg;&lt;br /&gt;
AT IPOM-PLASTIC&amp;#39;S RELAPSES</article-title><trans-title-group xml:lang="en"><trans-title>THE TISSUE PATHOMORPHOSIS AROUND THE MESH REPEREN&amp;reg;&lt;br /&gt;
AT IPOM-PLASTIC&amp;#39;S RELAPSES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Khitaryan</surname><given-names>A. G.</given-names></name><name xml:lang="en"><surname>Khitaryan</surname><given-names>A. G.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Kislyakov</surname><given-names>V. N.</given-names></name><name xml:lang="en"><surname>Kislyakov</surname><given-names>V. N.</given-names></name></name-alternatives><email>kislyackow.w@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shtilman</surname><given-names>M. Y.</given-names></name><name xml:lang="en"><surname>Shtilman</surname><given-names>M. Y.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Chumburidze</surname><given-names>I. P.</given-names></name><name xml:lang="en"><surname>Chumburidze</surname><given-names>I. P.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Voronova</surname><given-names>O. V.</given-names></name><name xml:lang="en"><surname>Voronova</surname><given-names>O. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>-</surname><given-names>- А.</given-names></name><name xml:lang="en"><surname>-</surname><given-names>-</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Kovalyov</surname><given-names>S. A.</given-names></name><name xml:lang="en"><surname>Kovalyov</surname><given-names>S. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Orekhov</surname><given-names>A. A.</given-names></name><name xml:lang="en"><surname>Orekhov</surname><given-names>A. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Alibekov</surname><given-names>A. Z.</given-names></name><name xml:lang="en"><surname>Alibekov</surname><given-names>A. Z.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="epub"><year>2020</year></pub-date><volume>43</volume><issue>1</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/journal-medicine/2020/1/135-145.pdf" /><abstract xml:lang="ru"><p>Intraperitoneal on-lay mesh (IPOM) laparoscopic hernioplasties using REPEREN&amp;reg; (Russia) mesh were performed at 103 patients with ventral hernias in the surgical department the Road Clinical Hospital at st. Rostov-Glavny from January 2015 to December 2018. The analysis of IPOM-plastic&amp;#39;s using REPEREN&amp;reg; mesh immediate and long-term results in patients with hernia area up to 100 cm2 showed good results: no intraoperative and postoperative complications, no pain after surgery, short hospitalization period (average 3.2 days) and rapid rehabilitation (on average, patients resumed normal work within 14 days). In the observation period of up to 1.5 years, no relapse was detected. With a primary hernia defect of &amp;ge;100 cm2, relapses were detected in 6 (6.18 %) patients over a period of 3 to 24 months. These patients underwent various consequent surgeries with the removal of the composite prostheses, which were subsequently subjected to morphological (macro- and microscopic) study. Macroscopic examination in all cases showed no compact adhesions between the loops of the intestines and the gel surface of the prosthesis and no dense scar tissue between the adhesive surface of the prosthesis and the anterior abdominal wall. Also, &amp;laquo;wrinkling&amp;raquo; of the prosthesis to 21.3 % of its original area was noted. Microscopic&amp;nbsp;prosthesis&amp;#39;s examination showed fibroblast migration, unstructured collagen fiber formation without connective tissue scar formation and insignificant leukocyte&amp;#39;s reaction.</p></abstract><trans-abstract xml:lang="en"><p>Intraperitoneal on-lay mesh (IPOM) laparoscopic hernioplasties using REPEREN&amp;reg; (Russia) mesh were performed at 103 patients with ventral hernias in the surgical department the Road Clinical Hospital at st. Rostov-Glavny from January 2015 to December 2018. The analysis of IPOM-plastic&amp;#39;s using REPEREN&amp;reg; mesh immediate and long-term results in patients with hernia area up to 100 cm2 showed good results: no intraoperative and postoperative complications, no pain after surgery, short hospitalization period (average 3.2 days) and rapid rehabilitation (on average, patients resumed normal work within 14 days). In the observation period of up to 1.5 years, no relapse was detected. With a primary hernia defect of &amp;ge;100 cm2, relapses were detected in 6 (6.18 %) patients over a period of 3 to 24 months. These patients underwent various consequent surgeries with the removal of the composite prostheses, which were subsequently subjected to morphological (macro- and microscopic) study. Macroscopic examination in all cases showed no compact adhesions between the loops of the intestines and the gel surface of the prosthesis and no dense scar tissue between the adhesive surface of the prosthesis and the anterior abdominal wall. Also, &amp;laquo;wrinkling&amp;raquo; of the prosthesis to 21.3 % of its original area was noted. Microscopic&amp;nbsp;prosthesis&amp;#39;s examination showed fibroblast migration, unstructured collagen fiber formation without connective tissue scar formation and insignificant leukocyte&amp;#39;s reaction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ventral hernia</kwd><kwd>hernia's relapse</kwd><kwd>IPOM laparoscopic hernioplasty</kwd><kwd>prosthesis REPEREN®</kwd><kwd>morphological examination</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ventral hernia</kwd><kwd>hernia's relapse</kwd><kwd>IPOM laparoscopic hernioplasty</kwd><kwd>prosthesis REPEREN®</kwd><kwd>morphological examination</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>1. Agaev B.A., Rustamov E.G., Rustamov G.A. 2009. Laparoskopicheskaja plastika brjushnoj stenki pri posleoperacionnyh ventral&amp;#39;nyh gryzhah [Laparoscopic abdominal wall repair in postoperative ventral hernia]. 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