Список литературы

2687-0940

Challenges in modern medicine

2687-0940

10.52575/2687-0940-2023-46-1-79-91

146

SURGERY

<strong>The Use of Biodegradable Wound Dressing in the Treatment of Donor and Burn Wounds in Patients with Thermal Injury</strong>

Borisov

Valery S.

Borisov

Valery S.

BorisovVS@mail.ru

Borovkova

Natalia V.

Borovkova

Natalia V.

Sachkov

Aleksey V.

Sachkov

Aleksey V.

Kaplunova

Maria Yu.

Kaplunova

Maria Yu.

Andreev

Yuliy V.

Andreev

Yuliy V.

Zhirkova

Elena A.

Zhirkova

Elena A.

Titova

Galina P.

Titova

Galina P.

Smirnov

Kirill S.

Smirnov

Kirill S.

Makarova

Maria Y.

Makarova

Maria Y.

2023

46100

We have undertaken a prospective analysis of 50 patients with burns in the topical treatment of which «ChitoPran» biodegradable coatings were used. The conditions for the most effective use of «ChitoPran» have been identified. The technique of optimal wound management after the application of «ChitoPran» is presented. The main errors in the application of wound dressing are noted. The clinical efficacy of «ChitoPran» was shown in comparison with traditional treatment: in patients with «ChitoPran» of the period of epithelialization of donor wounds were statistically significantly reduced (up to 8 days, instead of 11 days), the frequency of infectious complications decreased to 15 %, instead of 25 %. Pain intensity according to VAS decreased to 2 points instead of 5 points with traditional treatment, which allowed for earlier activation of patients. When using ChitoPran, histological analysis of the skin structure confirmed the development of a full-fledged epithelium.

wound dressingsburnsdonor woundschitosan

Список литературы

Alekseev A.A. 2020. Osnovnye statisticheskie pokazateli raboty meditsinskikh organizatsiy Rossii po okazaniyu spetsializirovannoy meditsinskoy pomoshchi postradavshim ot ozhogov v 2019 godu [The main statistical indicators of the work of medical organizations in Russia to provide specialized medical care to victims of burns in 2019]. Protokol zasedaniya profil'noy komissii po kombustiologii Minzdrava Rossii sovmestno s Plenumom Obshcherossiyskoy obshchestvennoy organizatsii «Ob"edinenie kombustiologov «Mir bez ozhogov», 29 oktyabrya 2020 g. Available at: http://combustiolog.ru/news_site/zasedaniya-profil-noj-komissii-po-kombustiologii-minzdrava-rossii-sovmestno-s-plenumom-obshherossijskoj-obshhestvennoj-organizatsii-ob-edinenie-kombustiologov-mir-bez-ozhogov-29-10-2020/ (accessed 14 Sept 2022).

Atjasov N.I. 1989. Lechenie ran donorskih uchastkov pri svobodnoj kozhnoj plastike u obozhzhjonnyh [Treatment of wounds of donor sites with free skin grafting in burnt patients]. Saransk: MGU, 91.

Bogdanov S.B., Karakulev A.V., Gilevich I.V., Melkonyan K.I., Polyakov A.V., Sotnichenko A.S. 2020. Opyt primeneniya ranevogo pokrytiya «KhitoPran» pri lechenii patsiyenta s kombinirovannoy travmoy [The experience of using «chitopran» wound coating for treating a patient with combined injury]. Ortopediya, travmatologiya i vosstanovitel'naya khirurgiya detskogo vozrasta, 8 (3): 327–332.

Borisov V.S., Afanasov I.M., Filatov I.Yu., Kaplunova M.Yu., Loginov L.P., Smirnov K.S. 2017. Ispol'zovaniye zamenitelya kozhi pri lechenii donorskikh uchastkov [The use of skin substitute in the treatment of donor sites]. V: Abstr. 17-y Kongress Yevropeyskoy assotsiatsii ozhogov EBA (Barselona, Ispaniya, 6–9 sentyabrya 2017 g.): 71. #026.02.

Budkevich L.I., Mirzoyan G.V., Gabitov R.B., Brazol M.A., Salistyj P.V., Chikinev Y.V., Shmyrin A.A., Glutkin A.V. 2020. Bioplasticheskiy kollagenovyy material «Kollost» pri lechenii ozhogovoy travmy [Сollost bioplastic collagen material for the treatment of burns]. Sovremennye tekhnologii v meditsine, 12 (1): 92–97.

Krajnjukov P.E., Zinov'ev E.V., Osmanov K.F. 2018. Osobennosti klinicheskoy kartiny i rezul'taty lecheniya donorskikh ran posle autodermoplastiki u postradavshikh ot ozhogov [Features of the clinical picture and results of treatment of donor wounds after autodermoplasty in victims of burns]. Vestnik Nacional'nogo mediko-hirurgicheskogo Centra im. N.I. Pirogova, 13 (2): 113–117.

Kuznetsova T.A., Besednova N.N., Usov V.V., Andryukov B.G. 2020. Biosovmestimyye i biodegradiruyemyye ranevyye pokrytiya na osnove polisakharidov iz morskikh vodorosley (obzor literatury) [Biocompatible and biodegradable wound dressings on the basis of seaweed polysaccharides (review of literature)]. Vestnik khirurgii im. I.I. Grekova, 179 (4): 109–115. doi: 10.24884/0042-4625-2020-179-4-109-115

Polyakov A.V., Bogdanov S.B., Afanasov I.M., Karakulev A.V., Bogdanova Y.A., Zinoviev E.V., Osmanov K.F. 2019. Ispol'zovaniye ranevykh pokrytiy na osnove khitozana «Khitopran» v lechenii bol'nykh s ozhogovoy travmoy [Application of chitosan-based wound coatings ‘chitopran’ in the treatment of patients with burn trauma]. Innovatsionnaya meditsina Kubani, 3 (15): 25–31. doi: 10.35401/2500-0268-2019-15-3-25-31

Potekaev N.N., Frigo N.V., Petersen E.V. 2017. Iskusstvennaya kozha: vidy, oblasti primeneniya [Artificial skin: types and applications]. Klinicheskaya dermatologiya i venerologiya, 16 (6): 7–15. doi: 10.17116/klinderma20171667-15

Abdel-Sayed P., Michetti M., Scaletta C., Flahaut M., Hirt-Burri N., de Buys Roessingh A., Raffoul W., Applegate L.A. 2019. Cell therapies for skin regeneration: an overview of 40 years of experience in burn units. Swiss. Med. Wkly. 149: w20079. doi: 10.4414/smw.2019.20079

Asuku M., Yu T.C., Yan Q., Böing E., Hahn H., Hovland S., Donelan M.B. 2021. Split-thickness skin graft donor-site morbidity: A systematic literature review. Burns. 47 (7): 1525–1546. doi: 10.1016/j.burns.2021.02.014

Dai T., Tanaka M., Huang Y.Y., Hamblin M.R. 2011. Chitosan preparations for wounds and burns: Antimicrobial and wound-healing effects. Expert Rev. Anti-Infect. Ther. 9 (Is7): 857–879. doi: 10.1586/eri.11.59

Devi N., Dutta J. 2017. Preparation and Characterization of Chitosan-bentonite Nanocomposite Films for Wound Healing Application. Int. J. Biol. Macromol. 104 (Pt B): 1897–1904. doi: 10.1016/j.ijbiomac.2017.02.080

Halim A.S., Khoo T.L., Mohd Yussof S.J. 2010. Biologic and synthetic skin substitutes: An overview. Indian. J. Plast.Surg. 43 (Suppl): 23–28. doi: 10.4103/0970-0358.70712

Huskisson E.C. 1974. Measurement of pain. Lancet. 2 (7889): 1127–1131. doi: 10.1016/s0140-6736(74)90884-8

Luca-Pozner V., Nischwitz S.P., Conti E., Lipa G., Ghezal S., Luze H., Funk M., Remy H., Qassemyar Q. 2022. The use of a novel burn dressing out of bacterial nanocellulose compared to the French standard of care in paediatric 2nd degree burns – A retrospective analysis. Burns. 48 (6):

1472–1480. doi: 10.1016/j.burns.2021.11.019

Schiefer J.L., Aretz G.F., Fuchs P.C., Bagheri M., Funk M., Schulz A., Daniels M. 2022. Comparison of wound healing and patient comfort in partial-thickness burn wounds treated with SUPRATHEL and epicte hydro wound dressings. Int. Wound. J. 19 (4): 782–790. doi: 10.1111/iwj.13674

Yamakawa S., Hayashida K. 2019. Advances in surgical applications of growth factors for wound healing. Burns Trauma. 7: 10. doi: 10.1186/s41038-019-0148-1

You C., Li Q., Wang X., Wu P., Ho J.K., Jin R., Zhang L., Shao H., Han C. 2017. Silver Nanoparticle Loaded Collagen/chitosan Scaffolds Promote Wound Healing via Regulating Fibroblast Migration and Macrophage Activation. Sci. Rep. 7 (1):10489. doi: 10.1038/s41598-017-10481-0

Zulfiqar Ali Khan, Shahrin Jamil, Amna Akhtar, Muhammad Mustehsan Bashir, Muhammad Yar. 2020. Chitosan based hybrid materials used for wound healing applications – A short review. Int. J. Polymeric. Materials Polymeric. Biomaterialis. 69 (7): 1–18. doi: 10.1080/00914037.2019.1575828