Medical communities in different countries are increasingly expressing interest in cellular technologies. The use of the patient's own biological material in the treatment of various diseases is a prospect of the future. Thus, the use of APRF – advanced platelet-rich fibrin clots in the treatment of various wound defects is both an alternative to more expensive techniques and safer for the patient. Their use is described in various fields of medicine, as they have a number of useful properties: local immunomodulatory, anti-inflammatory and regenerative effect. This article presents an overview of national and foreign literature in scope of advanced platelet-rich fibrin clots in the treatment of various wound defects, which can be effective for introduction and use in practice by surgeons, dentists, traumatologists.
Medical communities in different countries are increasingly expressing interest in cellular technologies. The use of the patient's own biological material in the treatment of various diseases is a prospect of the future. Thus, the use of APRF – advanced platelet-rich fibrin clots in the treatment of various wound defects is both an alternative to more expensive techniques and safer for the patient. Their use is described in various fields of medicine, as they have a number of useful properties: local immunomodulatory, anti-inflammatory and regenerative effect. This article presents an overview of national and foreign literature in scope of advanced platelet-rich fibrin clots in the treatment of various wound defects, which can be effective for introduction and use in practice by surgeons, dentists, traumatologists.